Green supported liquid membranes: The permeability activity-based linear operation (PABLO) method

Supported liquid membranes (SLMs) containing novel green solvents are proposed as a sustainable alternative separation process in the recovery of biomolecules. In this work, succinic acid has been successfully extracted from model fermentation broths through stripping phase-facilitated transport mechanism with four different supported membranes: two eutectic (DL-menthol:OctA and N4444Cl:OctA), bio-based solvent eucalyptol ionic [C4pyrr][Tf2N]. A permeability activity-based that takes into account for first time solute-phase affinities developed using quantum chemical COSMO-RS method; corrects mass transfer driving force allows extraction predictions beyond concentration equilibrium. The best achieved experimentally eucalyptol-based SLM (concentration factor 1.4) an alkaline aqueous solution (0.5 M NaOH) phase. countercurrent cascade design is proposed, graphical method to determine stage number, interstage concentrations well area requirements presented. This new tool, Permeability Activity-Based Linear Operation (PABLO) method, will substantially enhance SLMs technology biorefinery industry.